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ASAH1 抗体 (N-Term)

Cited in 2+ publications. This 兔 多克隆 anti-ASAH1 antibody specifically detects ASAH1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 和 兔 samples.
产品编号 ABIN2787375
发货至: 中国
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Quick Overview for ASAH1 抗体 (N-Term) (ABIN2787375)

抗原

See all ASAH1 抗体
ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

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克隆类型

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多克隆

标记

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This ASAH1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MPGRSCVALV LLAAAVSCAV AQHAPPWTED CRKSTYPPSG PTYRGAVPWY

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ASAH1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ASAH1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 395 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tan, Liu, Fox, Barth, Sharma, Turner, Awwad, Dewey, Doi, Spitzer, Shah, Morad, Desai, Amin, Zhu, Liao, Yun, Kester, Claxton, Wang, Cabot, Schuchman, Levine, Feith, Loughran: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).

    Elamin, Titz, Dijon, Merg, Geertz, Schneider, Martin, Schlage, Frentzel, Talamo, Phillips, Veljkovic, Ivanov, Vanscheeuwijck, Peitsch, Hoeng: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).

  • 抗原

    ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))

    别名

    ASAH1

    背景

    This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into
    Alias Symbols: AC, ASAH, FLJ21558, FLJ22079, PHP, PHP32, ACDase
    Protein Interaction Partner: SRPK1, CAMK1D, FBXO6, UBC, PSMA3, Bub1b, TSC22D1, SETDB1, SMPD1,
    Protein Size: 395

    分子量

    44 kDa

    基因ID

    427

    NCBI登录号

    NM_177924, NP_808592

    UniProt

    Q13510
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