ASAH1 抗体 (N-Term)
Quick Overview for ASAH1 抗体 (N-Term) (ABIN2787375)
抗原
See all ASAH1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- MPGRSCVALV LLAAAVSCAV AQHAPPWTED CRKSTYPPSG PTYRGAVPWY
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against ASAH1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ASAH1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 395 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).
: "
-
Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
-
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
-
别名
- ASAH1
-
背景
-
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into
Alias Symbols: AC, ASAH, FLJ21558, FLJ22079, PHP, PHP32, ACDase
Protein Interaction Partner: SRPK1, CAMK1D, FBXO6, UBC, PSMA3, Bub1b, TSC22D1, SETDB1, SMPD1,
Protein Size: 395 -
分子量
- 44 kDa
-
基因ID
- 427
-
NCBI登录号
- NM_177924, NP_808592
-
UniProt
- Q13510
抗原
-