PDE8A 抗体 (C-Term)
Quick Overview for PDE8A 抗体 (C-Term) (ABIN2787371)
抗原
See all PDE8A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- SSNPYHNSTH SADVLHATAY FLSKERIKET LDPIDEVAAL IAATIHDVDH
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
-
产品特性
- This is a rabbit polyclonal antibody against PDE8A. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PDE8A
-
-
anti-phosphodiesterase 8A (PDE8A) (AA 32-121) antibody
PDE8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 596-829) antibodyPDE8A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 681-730) antibodyPDE8A 适用: 人, 小鼠, 大鼠, 猴, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 551-600) antibodyPDE8A 适用: 人, 大鼠, 猴, 兔, 犬, 马, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) antibodyPDE8A 适用: 人 WB 宿主: 小鼠 Monoclonal EM-52 unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 1-829) antibodyPDE8A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (AA 1-120) antibodyPDE8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) antibodyPDE8A 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (C-Term) antibodyPDE8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8A (PDE8A) (C-Term) antibodyPDE8A 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, Pig, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 829 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- PDE8A (phosphodiesterase 8A (PDE8A))
-
别名
- PDE8A
-
背景
-
Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., MIM 2000).
Alias Symbols: FLJ16150, HsT19550
Protein Interaction Partner: UBC,
Protein Size: 829 -
分子量
- 91 kDa
-
基因ID
- 5151
-
NCBI登录号
- NM_002605, NP_002596
-
UniProt
- O60658
-
途径
- cAMP Metabolic Process
抗原
-
