CARD9 抗体 (Middle Region)
Quick Overview for CARD9 抗体 (Middle Region) (ABIN2787348)
抗原
See all CARD9 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- ALHQEQVLRN PHDAGLSSGE PPEKERRRLK ESFENYRRKR ALRKMQKGWR
-
预测反应
- Dog: 92%, Horse: 86%, Human: 100%, Mouse: 90%
-
产品特性
- This is a rabbit polyclonal antibody against CARD9. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CARD9
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 536 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
-
别名
- CARD9
-
背景
-
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
Alias Symbols: hCARD9, CANDF2
Protein Interaction Partner: KRTAP10-3, MFAP1, MEOX2, LMO1, ABLIM1, KRT31, KRT19, PHC2, DAXX, TRIM23, AES, KRTAP10-5, KRTAP10-1, CCDC36, TRIM42, CEP57L1, RTP5, PPP1R18, TCEANC, ALS2CR11, ZNF417, CWF19L2, ZNF572, KRT40, SSX2IP, PNMA5, C1orf94, ZNF587, LZTS2, ZCCHC7, FAM161A, CEP70, FA
Protein Size: 536 -
分子量
- 62 kDa
-
基因ID
- 64170
-
NCBI登录号
- NM_052813, NP_434700
-
UniProt
- Q9H257
-
途径
- Activation of Innate immune Response
抗原
-