SMEK1 抗体 (Middle Region)
Quick Overview for SMEK1 抗体 (Middle Region) (ABIN2787340)
抗原
See all SMEK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- YWKALEDVDY VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against SMEK1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SMEK1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 820 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
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别名
- SMEK1
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背景
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SMEK1 is the regulatory subunit of serine/threonine-protein phosphatase 4.SMEK1 may regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: FLFL1, KIAA2010, MSTP033, smk-1, smk1, PP4R3A
Protein Interaction Partner: HUWE1, UBC, PPP4R2, BRCC3, SF3A1, HNRNPR, TELO2, MTA2, PSMB1, PSMA2, DDB2, CAST, ARCN1, AMPD2, ACACA, CASK, POLR2A, IGBP1, PPP4C, HDAC1, MAPK14,
Protein Size: 820 -
分子量
- 94 kDa
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基因ID
- 55671
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NCBI登录号
- NM_032560, NP_115949
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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