MTRR 抗体 (N-Term)
(1 reference)-
- 抗原 See all MTRR 抗体
- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 兔, 大鼠, 犬, Cow, 豚鼠, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTRR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- YDLKTETAPL VVVVSTTGTG DPPDTARKFV KEIQNQTLPV DFFAHLRYGL
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MTRR. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MTRR
- Top Product
- Discover our top product MTRR Primary Antibody
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anti-5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 1-725) antibody
MTRR 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 1-110) antibodyMTRR 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 71-120) antibodyMTRR 适用: 人, 小鼠, 兔, 大鼠, 犬, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (AA 50-230) antibodyMTRR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 725 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects." in: Journal of cellular biochemistry, Vol. 114, Issue 1, pp. 183-91, (2012) (PubMed).
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: "Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects." in: Journal of cellular biochemistry, Vol. 114, Issue 1, pp. 183-91, (2012) (PubMed).
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- 抗原
- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
- 别名
- MTRR (MTRR 产品)
- 别名
- MSR antibody, 4732420G08 antibody, cblE antibody, MTRR antibody, 5-methyltetrahydrofolate-homocysteine methyltransferase reductase antibody, Mtrr antibody, MTRR antibody, mtrr antibody
- 背景
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Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: MGC129643, MSR, cblE
Protein Interaction Partner: GMCL1, PAPSS1, HIST1H2AG, FH, ELAVL1, UBC, MMAB,
Protein Size: 725 - 分子量
- 80 kDa
- 基因ID
- 4552
- NCBI登录号
- NM_024010, NP_076915
- UniProt
- Q9UBK8
- 途径
- Methionine Biosynthetic Process
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