RPRD1B 抗体 (C-Term)
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- 抗原 See all RPRD1B 抗体
- RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPRD1B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QERSVYGGEF IQQLKLSMED SKSPPPKAAE EKKSLKRTFQ QIQEEEDDDY
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Rprd1b. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Rprd1b
- Top Product
- Discover our top product RPRD1B Primary Antibody
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anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 1-326) antibody
RPRD1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 2-172) antibodyRPRD1B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 143-192) antibodyRPRD1B 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠, 小鸡, Hamster, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 254-282), (C-Term) antibodyRPRD1B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB25222 unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 261-290), (C-Term) antibodyRPRD1B 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
- 别名
- Rprd1b (RPRD1B 产品)
- 别名
- fb23h08 antibody, zgc:55687 antibody, wu:fb23h08 antibody, rprd1ba antibody, MGC130705 antibody, C13H20ORF77 antibody, C20orf77 antibody, CREPT antibody, NET60 antibody, dJ1057B20.2 antibody, 2610304G08Rik antibody, 2810446G03Rik antibody, Crept antibody, RGD1304782 antibody, regulation of nuclear pre-mRNA domain containing 1B antibody, regulation of nuclear pre-mRNA domain containing 1B L homeolog antibody, rprd1b antibody, rprd1b.L antibody, RPRD1B antibody, Rprd1b antibody
- 背景
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Rprd1b interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. It is a transcriptional regulator which enhances expression of CCND1. It promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. It prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. It also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Rprd1b promotes cell proliferation.
Alias Symbols: 2610304G08Rik, 2810446G03Rik, Crept
Protein Size: 224 - 分子量
- 24 kDa
- 基因ID
- 70470
- NCBI登录号
- NM_027434, NP_081710
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