TRIB3 抗体 (N-Term)
Quick Overview for TRIB3 抗体 (N-Term) (ABIN2787259)
抗原
See all TRIB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- YVLLEPEEGG RAYQALHCPT GTEYTCKVYP VQEALAVLEP YARLPPHKHV
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预测反应
- Cow: 79%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Rabbit: 86%, Rat: 79%, Sheep: 79%
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产品特性
- This is a rabbit polyclonal antibody against TRIB3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIB3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 358 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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别名
- TRIB3
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背景
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The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.
Alias Symbols: C20orf97, NIPK, SINK, SKIP3, TRB3
Protein Interaction Partner: RPGRIP1, UBC, DDIT3, ATF4, RFWD2, PRMT5, AKT1, APP, SMURF1, CDC25A, BMPR2, SMAD3, BCL6, COPS6, RBM48, EEF1G, SETDB1, GIT1, GDF9, KAT5, AKT2, RELA, ATF5, HRSP12, TIAF1, MCM3AP, LTBP4, SIAH1, RBM4, PSMA3, RPSA, HLA-B, GRN, FN1, CSNK2B,
Protein Size: 358 -
分子量
- 39 kDa
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基因ID
- 57761
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NCBI登录号
- NM_021158, NP_066981
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UniProt
- Q96RU7
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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