CALCOCO1 抗体 (N-Term)
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北京 101111
Quick Overview for CALCOCO1 抗体 (N-Term) (ABIN2787240)
抗原
See all CALCOCO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ESTTDGSPIH TSVQFQASYL PKPGAQLYQF RYVNRQGQVC GQSPPFQFRE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against CALCOCO1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CALCOCO1
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anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) (AA 462-691) antibody
CALCOCO1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) antibodyCALCOCO1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) (AA 1-691) antibodyCALCOCO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) antibodyCALCOCO1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) antibodyCALCOCO1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) (AA 71-120) antibodyCALCOCO1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 691 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))
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别名
- CALCOCO1
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背景
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CALCOCO1 functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR).CALCOCO1 is recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation CALCOCO1 acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. CALCOCO1 is involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. CALCOCO1 functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions.
Alias Symbols: Cocoa, KIAA1536, PP13275, calphoglin
Protein Interaction Partner: CWF19L2, CEP19, FAM161A, TBC1D15, DUSP13, ISOC1, GABARAPL2, NDC80, UBC, GRIK2, APP, APTX, EP300, CTNNB1, NEDD4, HIST1H4A, HIST1H3A, PCBD1, TBC1D17, CTNNBL1, CYTH3, SH3GL3, CRYBA2, CREBBP, MAPK1, KRT15, IPP, FOSL1,
Protein Size: 691 -
分子量
- 77 kDa
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基因ID
- 57658
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NCBI登录号
- NM_020898, NP_065949
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UniProt
- Q9P1Z2
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding
抗原
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