CDCA7L 抗体 (Middle Region)
Quick Overview for CDCA7L 抗体 (Middle Region) (ABIN2787158)
抗原
See all CDCA7L 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- PPCRGICNCS YCRKRDGRCA TGILIHLAKF YGYDNVKEYL ESLQKELVED
-
预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%, Zebrafish: 93%
-
产品特性
- This is a rabbit polyclonal antibody against CDCA7L. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CDCA7L
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 420 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))
-
别名
- CDCA7L
-
背景
-
CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.CDCA7L plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. CDCA7L is involved in apoptotic signaling pathways. CDCA7L may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Alias Symbols: DKFZp762L0311, JPO2, R1, RAM2
Protein Interaction Partner: KRTAP10-7, TRIM42, MORN3, BEND7, FAM9B, DEDD2, SSX2IP, ING5, TRAF3IP3, CEP70, CCDC33, CARD9, PRDM14, ZNF250, UTP3, CTNNBL1, ZNF821, CDCA7L, TFPT, ABT1, PRPF31, PPP1R16B, EIF4A3, STX11, UBL4A, TADA2A, NOP2, MFAP1, MDFI, LMO1, DAXX, BYSL, ANKRD11, SUV39H1,
Protein Size: 420 -
分子量
- 46 kDa
-
基因ID
- 55536
-
NCBI登录号
- NM_001127370, NP_001120842
-
UniProt
- B3KTR5
抗原
-