Tescalcin 抗体 (C-Term)
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Quick Overview for Tescalcin 抗体 (C-Term) (ABIN2787042)
抗原
See all Tescalcin (TESC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- DSDGRITLEE YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%
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产品特性
- This is a rabbit polyclonal antibody against TESC. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human TESC
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anti-Tescalcin (TESC) (AA 2-214) antibody
TESC 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tescalcin (TESC) (AA 88-116), (C-Term) antibodyTESC 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB25637 unconjugated
anti-Tescalcin (TESC) (AA 88-116), (C-Term) antibodyTESC 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Tescalcin (TESC)
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别名
- TESC
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背景
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TESC functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. It promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane and promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. It is essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. It is also involved in granulocytic differentiation in a ERK-dependent manner and inhibits the phosphatase activity of calcineurin.
Alias Symbols: CHP3, TSC
Protein Interaction Partner: WBP11, UBC, CCDC91, HMG20A, TESC, RAI1, DYNLT3, SLC9A1,
Protein Size: 214 -
分子量
- 23 kDa
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基因ID
- 54997
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NCBI登录号
- NM_017899, NP_060369
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UniProt
- Q96BS2
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途径
- Proton Transport
抗原
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