NLRP2 抗体 (C-Term)
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Quick Overview for NLRP2 抗体 (C-Term) (ABIN2787038)
抗原
See all NLRP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FETLTCSSGT LRTLRLKIDD FNDELNKLLE EIEEKNPQLI IDTEKHHPWA
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against NLRP2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NLRP2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1062 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
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别名
- NLRP2
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背景
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NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1, MIM 147678) by Toll-like receptors (see TLR4, MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).
Alias Symbols: CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2
Protein Interaction Partner: SUGT1, APP, FAF1, PYCARD, IKBKG, IKBKB, CHUK, HSP90AA1, UBC, MRE11A, PYDC2, CARD8,
Protein Size: 1062 -
分子量
- 120 kDa
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基因ID
- 55655
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NCBI登录号
- NM_017852, NP_060322
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UniProt
- Q9NX02
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途径
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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