Nemo-Like Kinase 抗体 (Middle Region)
Quick Overview for Nemo-Like Kinase 抗体 (Middle Region) (ABIN2786944)
抗原
See all Nemo-Like Kinase (NLK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RLRYHTCMCK CCFSTSTGRV YTSDFEPVTN PKFDDTFEKN LSSVRQVKEI
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against NLK. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NLK
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anti-Nemo-Like Kinase (NLK) (AA 416-515) antibody
NLK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Nemo-Like Kinase (NLK) antibodyNLK 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) antibodyNLK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 278-527) antibodyNLK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 278-527) antibodyNLK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 1-515) antibodyNLK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (N-Term) antibodyNLK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 408-436), (C-Term) antibodyNLK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34651 unconjugated
anti-Nemo-Like Kinase (NLK) (AA 275-300) antibodyNLK 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB16621 unconjugated
anti-Nemo-Like Kinase (NLK) (Thr286) antibodyNLK 适用: 人 WB, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 527 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Nemo-Like Kinase (NLK)
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别名
- NLK
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背景
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NLK has a role in cell fate determination, required for differentiation of bone marrow stromal cells. NLK acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. NLK may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP By similarity.NLK is involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Alias Symbols: DKFZp761G1211, FLJ21033
Protein Interaction Partner: KRTAP5-6, KRTAP10-3, KRTAP4-2, QRICH1, ZHX3, KRTAP5-9, GRN, TP53, MDM2, STAT5A, LEF1, CNOT2, SMAD4, KPNB1, BACH1, TNKS1BP1, FAM222A, C2orf44, CEP97, RNF219, FAM222B, CNOT11, NLK, PASK, SHANK2, UBAP2L, CCP110, TRPS1, TLE3, SKI, RANGAP1, RANBP2, PKM, CNOT3,
Protein Size: 527 -
分子量
- 58 kDa
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基因ID
- 51701
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NCBI登录号
- NM_016231, NP_057315
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UniProt
- Q9UBE8
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途径
- Ubiquitin Proteasome Pathway
抗原
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