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- 抗原 See all PRR5 抗体
- PRR5 (Proline Rich 5 (Renal) (PRR5))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRR5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD
- 预测反应
- Cow: 100%, Dog: 91%, Horse: 86%, Human: 100%, Pig: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PRR5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PRR5
- Top Product
- Discover our top product PRR5 Primary Antibody
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anti-Proline Rich 5 (Renal) (PRR5) (AA 109-388) antibody
PRR5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (AA 35-84) antibodyPRR5 适用: 人, 马, 兔, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (C-Term) antibodyPRR5 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (N-Term) antibodyPRR5 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 379 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PRR5 (Proline Rich 5 (Renal) (PRR5))
- 别名
- PRR5 (PRR5 产品)
- 别名
- AU043908 antibody, Arhgap8 antibody, C030017C09Rik antibody, C78947 antibody, Protor-1 antibody, Protor1 antibody, FLJ20185k antibody, PP610 antibody, PROTOR-1 antibody, PROTOR1 antibody, pp610 antibody, protor1 antibody, protor2 antibody, proline rich 5 (renal) antibody, proline rich 5 antibody, proline rich 5 L homeolog antibody, Prr5 antibody, PRR5 antibody, prr5.L antibody
- 背景
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This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Alias Symbols: PP610, PROTOR1, PROTOR-1, FLJ20185k,
Protein Interaction Partner: MTOR, BRCA1, UBC, RICTOR, MAPKAP1, MLST8,
Protein Size: 293 - 分子量
- 32 kDa
- 基因ID
- 55615
- NCBI登录号
- NM_001017528, NP_056181
- 途径
- PI3K-Akt Signaling
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