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PKC eta 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects PKC eta in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 斑马鱼 和 Pig.
产品编号 ABIN2786852
发货至: 中国
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Quick Overview for PKC eta 抗体 (N-Term) (ABIN2786852)

抗原

See all PKC eta (PRKCH) 抗体
PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

适用

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人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 斑马鱼, Pig

宿主

  • 80
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兔

克隆类型

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多克隆

标记

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This PKC eta antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    原理

    PRKCH Antibody - N-terminal region

    序列

    KKGHQLLDPY LTVSVDQVRV GQTSTKQKTN KPTYNEEFCA NVTDGGHLEL

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against PRKCH. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCH
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56703-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

    别名

    PRKCH

    背景

    Background Information: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

    Gene Name: Protein kinase C, eta

    Alternative Symbols: PKCL, PKC-L, PRKCL, nPKC-eta

    Protein Name: Protein kinase C eta type

    分子量

    78 kDa

    基因ID

    5583

    NCBI登录号

    NP_006246

    UniProt

    P24723

    途径

    Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
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