PKC eta 抗体 (N-Term)
Quick Overview for PKC eta 抗体 (N-Term) (ABIN2786852)
抗原
See all PKC eta (PRKCH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KKGHQLLDPY LTVSVDQVRV GQTSTKQKTN KPTYNEEFCA NVTDGGHLEL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against PRKCH. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCH
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anti-Protein Kinase C, eta (PRKCH) (AA 1-678) antibody
PRKCH 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 1-100) antibodyPRKCH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 1-683) antibodyPRKCH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 210-239), (N-Term) antibodyPRKCH 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 355-614) antibodyPRKCH 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 35-84) antibodyPRKCH 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 斑马鱼, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 1-683) antibodyPRKCH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (N-Term) antibodyPRKCH 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (AA 517-566) antibodyPRKCH 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 马, 斑马鱼, Pig, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, eta (PRKCH) (C-Term) antibodyPRKCH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 683 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
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别名
- PRKCH
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背景
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Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
Alias Symbols: MGC26269, MGC5363, PKC-L, PKCL, PRKCL, nPKC-eta
Protein Interaction Partner: BANP, HSP90AA1, GSK3A, PPP1R14A, UBC, VHL, PRKCH, NFE2L2, MGMT, ZBTB8OS, PARD6A, PRKD1, NUMB, ITGB2, SRC, PTPN11, FYN, CDK2, PDPK1, AKAP13,
Protein Size: 683 -
分子量
- 78 kDa
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基因ID
- 5583
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NCBI登录号
- NM_006255, NP_006246
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UniProt
- P24723
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途径
- Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
抗原
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