Retinoblastoma Binding Protein 4 抗体 (C-Term)
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- 抗原 See all Retinoblastoma Binding Protein 4 (RBBP4) 抗体
- Retinoblastoma Binding Protein 4 (RBBP4)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Retinoblastoma Binding Protein 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TAKISDFSWN PNEPWVICSV SEDNIMQVWQ MAENIYNDED PEGSVDPEGQ
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Rbbp4. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Rbbp4
- Top Product
- Discover our top product RBBP4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 425 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Retinoblastoma Binding Protein 4 (RBBP4)
- 别名
- Rbbp4 (RBBP4 产品)
- 背景
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Rbbp4 is a core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.
Alias Symbols: mRbAp48
Protein Interaction Partner: L3mbtl2, E130012A19Rik, Hdac1, Nanog, Suz12, Tcf3, Runx1, HIST3H3, Kdm2b, Rnf2, Mta2, Gata1, Ezh1, Sall4, Esrrb, Mtf2, Jarid2, Ezh2, Eed,
Protein Size: 425 - 分子量
- 47 kDa
- 基因ID
- 19646
- NCBI登录号
- NM_009030, NP_033056
- UniProt
- Q60972
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus
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