SH3BP2 抗体 (Middle Region)
Quick Overview for SH3BP2 抗体 (Middle Region) (ABIN2786764)
抗原
See all SH3BP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ
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预测反应
- Cow: 85%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SH3BP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SH3BP2
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anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 452-561) antibody
SH3BP2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 432-481) antibodySH3BP2 适用: 人, 小鼠, 大鼠, 猴, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 165-301) antibodySH3BP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) antibodySH3BP2 适用: 小鼠 WB 宿主: 绵羊 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 1-561) antibodySH3BP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 2 (SH3BP2) (AA 392-561) antibodySH3BP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 561 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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别名
- SH3BP2
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背景
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SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism.
Alias Symbols: 3BP2, CRBM, CRPM, FLJ42079, RES4-23, 3BP-2
Protein Interaction Partner: RNF146, TNKS2, PDLIM7, TNKS, UBC, ERBB2, VAV1, SYK, SRC, CBL, SH3KBP1, DBNL, VAV3, LAT, VAV2, PLCG2, TF, ABL1, ZAP70, PLCG1, LCK, YWHAQ, FYN, FLT3, FGFR1, GRB2,
Protein Size: 561 -
分子量
- 62 kDa
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基因ID
- 6452
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NCBI登录号
- NM_003023, NP_003014
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UniProt
- P78314
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途径
- TCR Signaling
抗原
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