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P5CS 抗体 (N-Term)

ALDH18A1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786580
发货至: 中国
  • 抗原 See all P5CS (ALDH18A1) 抗体
    P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
    抗原表位
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 豚鼠, 兔, 斑马鱼
    宿主
    • 14
    • 4
    • 1
    克隆类型
    • 17
    • 2
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    This P5CS antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    SVIRHVRSWS NIPFITVPLS RTHGKSFAHR SELKHAKRIV VKLGSAVVTR
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against ALDH18A1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ALDH18A1
    Top Product
    Discover our top product ALDH18A1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 793 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
    别名
    ALDH18A1 (ALDH18A1 产品)
    别名
    ALDH18A1 antibody, ARCL3A antibody, GSAS antibody, P5CS antibody, PYCS antibody, 2810433K04Rik antibody, AI429789 antibody, Pycs antibody, cb842 antibody, cb899 antibody, pycs antibody, sb:cb881 antibody, wu:fa91f10 antibody, wu:fi05f11 antibody, wu:fi17d12 antibody, aldehyde dehydrogenase 18 family member A1 antibody, aldehyde dehydrogenase 18 family, member A1 antibody, aldehyde dehydrogenase 18 family member A1 L homeolog antibody, ALDH18A1 antibody, aldh18a1 antibody, Aldh18a1 antibody, aldh18a1.L antibody
    背景
    This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases.This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
    Alias Symbols: GSAS, MGC117316, P5CS, PYCS, ARCL3A
    Protein Interaction Partner: CMTM5, AGTRAP, UBC, SUMO2, SUMO3, STAU1, MDM2, LATS2, ADRB2, VCP, TIMM13, SUMO1, NONO, MTHFD1, ILF3, ILF2, DDX1, CUL3, CDK2, SIRT7, TCF3, Haus1, Mical3, Trim69, Cbx1, HDAC5, MYC, ICT1, ZRANB1,
    Protein Size: 793
    分子量
    87 kDa
    基因ID
    5832
    NCBI登录号
    NM_001017423, NP_001017423
    UniProt
    P54886
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