P5CS 抗体 (N-Term)
Quick Overview for P5CS 抗体 (N-Term) (ABIN2786580)
抗原
See all P5CS (ALDH18A1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SVIRHVRSWS NIPFITVPLS RTHGKSFAHR SELKHAKRIV VKLGSAVVTR
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against ALDH18A1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALDH18A1
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anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 696-795) antibody
ALDH18A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 176-205) antibodyALDH18A1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21608 unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 696-795) antibodyALDH18A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 1-795) antibodyALDH18A1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 35-84) antibodyALDH18A1 适用: 人, 小鼠, 大鼠, Cow, Pig, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 1-240) antibodyALDH18A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (N-Term) antibodyALDH18A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 793 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
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别名
- ALDH18A1
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背景
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This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases.This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
Alias Symbols: GSAS, MGC117316, P5CS, PYCS, ARCL3A
Protein Interaction Partner: CMTM5, AGTRAP, UBC, SUMO2, SUMO3, STAU1, MDM2, LATS2, ADRB2, VCP, TIMM13, SUMO1, NONO, MTHFD1, ILF3, ILF2, DDX1, CUL3, CDK2, SIRT7, TCF3, Haus1, Mical3, Trim69, Cbx1, HDAC5, MYC, ICT1, ZRANB1,
Protein Size: 793 -
分子量
- 87 kDa
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基因ID
- 5832
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NCBI登录号
- NM_001017423, NP_001017423
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UniProt
- P54886
抗原
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