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GOPC 抗体 (Middle Region)

This anti-GOPC antibody is a 兔 多克隆 antibody detecting GOPC in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠 和 马.
产品编号 ABIN2786579
发货至: 中国

Quick Overview for GOPC 抗体 (Middle Region) (ABIN2786579)

抗原

See all GOPC 抗体
GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

适用

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人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马

宿主

  • 71
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克隆类型

  • 62
  • 10
多克隆

标记

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This GOPC antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    RNDLKRPMQA PPGHDQDSLK KSQGVGPIRK VLLLKEDHEG LGISITGGKE

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GOPC. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human GOPC
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 454 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

    别名

    GOPC

    背景

    GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].
    Alias Symbols: CAL, FIG, GOPC1, PIST, dJ94G16.2
    Protein Interaction Partner: BATF, SSNA1, VTN, MYLK, HCK, FOSL2, DPYD, RPL13AP17, C17orf67, ZSCAN1, LCLAT1, FAM9B, ZBTB49, ZNF564, SPATA8, RNF183, MORN4, MYOCD, MUM1, ZNF587, SLC25A18, CCDC102B, AKIRIN1, MRPL1, SEMA4G, RNF220, FAM90A1, PID1, ZNF581, CERCAM, RHOQ, PARK7, STARD3, HSF1,
    Protein Size: 454

    分子量

    50 kDa

    基因ID

    57120

    NCBI登录号

    NM_001017408, NP_001017408

    UniProt

    Q9HD26

    途径

    Maintenance of Protein Location, Asymmetric Protein Localization
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