Rhotekin 抗体 (N-Term)
Quick Overview for Rhotekin 抗体 (N-Term) (ABIN2786576)
抗原
See all Rhotekin (RTKN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DSGPPAERSP CRGRVCISDL RIPLMWKDTE YFKNKGDLHR WAVFLLLQLG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against RTKN. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RTKN
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anti-Rhotekin (RTKN) antibody
RTKN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Rhotekin (RTKN) (AA 451-549) antibodyRTKN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Rhotekin (RTKN) (AA 304-563) antibodyRTKN 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Rhotekin (RTKN) (AA 254-513) antibodyRTKN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Rhotekin (RTKN) (AA 296-548) antibodyRTKN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rhotekin (RTKN) antibodyRTKN 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Rhotekin (RTKN) (AA 451-549) antibodyRTKN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Rhotekin (RTKN) (AA 451-550) antibodyRTKN 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Rhotekin (RTKN) (AA 431-480) antibodyRTKN 适用: 人, 大鼠, 小鼠, 犬, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Rhotekin (RTKN) (AA 107-156) antibodyRTKN 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 563 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Rhotekin (RTKN)
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别名
- RTKN
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背景
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RTKN mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. RTKN may play a novel role in the organization of septin structures.This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: -
Protein Interaction Partner: YWHAB, RHO1, APP, RHOA, UBC, TAX1BP3, SMURF1, GOPC, RAC2, TGFBR1, RHOC, RTN4R,
Protein Size: 563 -
分子量
- 63 kDa
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基因ID
- 6242
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NCBI登录号
- NM_001015055, NP_001015055
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UniProt
- Q9BST9
抗原
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