MVK 抗体 (N-Term)
Quick Overview for MVK 抗体 (N-Term) (ABIN2786518)
抗原
See all MVK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LAVLAFLYLY LSICRKQRAL PSLDIVVWSE LPPGAGLGSS AAYSVCLAAA
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against MVK. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MVK
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anti-Mevalonate Kinase (MVK) (AA 297-396) antibody
MVK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Mevalonate Kinase (MVK) (AA 297-396) antibodyMVK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) antibodyMVK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (Internal Region) antibodyMVK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (AA 1-396) antibodyMVK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) antibodyMVK 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (Internal Region) antibodyMVK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (AA 179-228) antibodyMVK 适用: 人, 小鼠, 猴, Cow, 犬, 兔, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (AA 107-156) antibodyMVK 适用: 人, 小鼠, 大鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (Internal Region) antibodyMVK 适用: 人, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 396 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MVK (Mevalonate Kinase (MVK))
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别名
- MVK
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背景
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MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.
Alias Symbols: LRBP, MVLK, MK
Protein Interaction Partner: MVK, PPP1CB, GSS, MAT1A, POT1, TERF1, UBC, EWSR1,
Protein Size: 396 -
分子量
- 42 kDa
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基因ID
- 4598
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NCBI登录号
- NM_000431, NP_000422
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UniProt
- Q03426
抗原
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