HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (N-Term) 抗体
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- 抗原 See all HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) 抗体
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 序列
- TGSPYSTNCW LCTSSSTETP GTAYPASPRE WTSIEAELHI SYRWDPNLKG
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HERV-FRD. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HERV-FRD
- Top Product
- Discover our top product Herv-frd Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 538 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta." in: Retrovirology, Vol. 5, pp. 6, (2008) (PubMed).
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Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta." in: Retrovirology, Vol. 5, pp. 6, (2008) (PubMed).
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- 抗原
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
- 别名
- HERV-FRD (Herv-frd 产品)
- 别名
- ERVFRDE1 antibody, GLLL6191 antibody, HERV-FRD antibody, HERV-W/FRD antibody, UNQ6191 antibody, envFRD antibody, Gm52 antibody, Syna antibody, endogenous retrovirus group FRD member 1, envelope antibody, ERVFRD-1 antibody, Ervfrd-1 antibody
- 物质类
- Viral Protein
- 背景
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Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8 % of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1, MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].
Alias Symbols: FLJ41944, FLJ90611, GLLL6191, MGC87585, UNQ6191, envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD
Protein Interaction Partner: APP,
Protein Size: 538 - 分子量
- 60 kDa
- 基因ID
- 405754
- NCBI登录号
- NM_207582, NP_997465
- UniProt
- P60508
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