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HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (N-Term) 抗体

Cited in 1 publication. The 兔 多克隆 anti-HERV-FRD Provirus Ancestral Env Polyprotein antibody (ABIN2786479) specifically detects HERV-FRD Provirus Ancestral Env Polyprotein in WB. The antibody is reactive with 人 samples.
产品编号 ABIN2786479
发货至: 中国
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Quick Overview for HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (N-Term) 抗体 (ABIN2786479)

抗原

See all HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) 抗体
HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

适用

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宿主

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克隆类型

  • 42
多克隆

标记

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非结合性

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    TGSPYSTNCW LCTSSSTETP GTAYPASPRE WTSIEAELHI SYRWDPNLKG

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against HERV-FRD. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HERV-FRD
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 538 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Malassiné, Frendo, Blaise, Handschuh, Gerbaud, Tsatsaris, Heidmann, Evain-Brion: "Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta." in: Retrovirology, Vol. 5, pp. 6, (2008) (PubMed).

  • 抗原

    HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

    别名

    HERV-FRD

    背景

    Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8 % of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1, MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].
    Alias Symbols: FLJ41944, FLJ90611, GLLL6191, MGC87585, UNQ6191, envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD
    Protein Interaction Partner: APP,
    Protein Size: 538

    分子量

    60 kDa

    基因ID

    405754

    NCBI登录号

    NM_207582, NP_997465

    UniProt

    P60508
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