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FBXO33 抗体 (Middle Region)

FBXO33 适用: 大鼠, 人, 小鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786447
发货至: 中国
  • 抗原 See all FBXO33 抗体
    FBXO33 (F-Box Protein 33 (FBXO33))
    抗原表位
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    大鼠, 人, 小鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼
    宿主
    • 20
    • 3
    克隆类型
    • 23
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO33 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    Western Blotting (WB)
    序列
    VIDTSGFPDL SDNRNEDPLV LLAWRCTKLS LLAIHGYTVW AHNLIAIARL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against FBXO33. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human FBXO33
    Top Product
    Discover our top product FBXO33 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 555 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FBXO33 (F-Box Protein 33 (FBXO33))
    别名
    FBXO33 (FBXO33 产品)
    别名
    FBXO33 antibody, BMND12 antibody, Fbx33 antibody, c14_5247 antibody, 5730501N20Rik antibody, AI642135 antibody, F-box protein 33 antibody, F-box protein 33 S homeolog antibody, FBXO33 antibody, fbxo33 antibody, fbxo33.S antibody, Fbxo33 antibody
    背景
    FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
    Alias Symbols: Fbx33, c14_5247, BMND12
    Protein Interaction Partner: CUL1, YBX1, UBC,
    Protein Size: 555
    分子量
    62 kDa
    基因ID
    254170
    NCBI登录号
    NM_203301, NP_976046
    UniProt
    Q7Z6M2
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