Carabin 抗体 (N-Term)
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北京 101111
Quick Overview for Carabin 抗体 (N-Term) (ABIN2786421)
抗原
See all Carabin (TBC1D10C) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MAQALGEDLV QPPELQDDSS SLGSDSELSG PGPYRQADRY GFIGGSSAEP
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Pig: 93%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against TBC1D10C. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TBC1D10C
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anti-TBC1 Domain Family, Member 10C (TBC1D10C) (Internal Region) antibody
Verified TBC1D10C 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) antibodyTBC1D10C 适用: 人, Cow, 大鼠, 犬, 豚鼠, 马, 猴, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) antibodyTBC1D10C 适用: 人, Cow, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 10C (TBC1D10C) (AA 14-236) antibodyTBC1D10C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 10C (TBC1D10C) (C-Term) antibodyTBC1D10C 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) antibodyTBC1D10C 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 446 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
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别名
- TBC1D10C
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背景
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TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM].
Alias Symbols: FLJ00332, MGC46488, EPI64C, CARABIN
Protein Interaction Partner: NOTCH2NL, KRTAP13-1, KLHL12, KRTAP5-9, HOXA1, APP, PPP3R2,
Protein Size: 446 -
分子量
- 50 kDa
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基因ID
- 374403
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NCBI登录号
- NM_198517, NP_940919
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UniProt
- Q8IV04
抗原
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