SPAG8 抗体 (Middle Region)
(1 reference)Quick Overview for SPAG8 抗体 (Middle Region) (ABIN2786290)
抗原
See all SPAG8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PAPTKPHDYR QEQPETFWIQ RAPQLPTWWP LPTQVPAAED YLTWKEWGFT
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预测反应
- Cow: 79%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SPAG8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SPAG8
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anti-Sperm Associated Antigen 8 (SPAG8) (AA 1-501) antibody
SPAG8 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 1-501) antibodySPAG8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 342-426) antibodySPAG8 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 236-409) antibodySPAG8 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 396-445) antibodySPAG8 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 143-192) antibodySPAG8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (AA 220-420) antibodySPAG8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (Middle Region) antibodySPAG8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (N-Term) antibodySPAG8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 8 (SPAG8) (N-Term) antibodySPAG8 适用: 人, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 501 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population." in: European journal of epidemiology, Vol. 23, Issue 1, pp. 23-7, (2008) (PubMed).
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: "The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population." in: European journal of epidemiology, Vol. 23, Issue 1, pp. 23-7, (2008) (PubMed).
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- SPAG8 (Sperm Associated Antigen 8 (SPAG8))
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别名
- SPAG8
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背景
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The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. SPAG8 is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
Alias Symbols: BS-84, HSD-1, MGC26201, SMP1, SPAG3, hSMP-1
Protein Interaction Partner: KLHL32, DTX2, SNRPC, CSTF2, PITX1, JMJD4, WHSC1L1, KDM3B, CARM1, PRMT5, PRMT1, PRMT2, RANBP9, UBQLN4, NEDD4L, RAN,
Protein Size: 501 -
分子量
- 53 kDa
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基因ID
- 26206
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NCBI登录号
- NM_172312, NP_758516
抗原
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