IL-15 抗体 (N-Term)
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- 抗原 See all IL-15 (IL15) 抗体
- IL-15 (IL15) (Interleukin 15 (IL15))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 兔, 绵羊, 豚鼠, Pig, 马, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-15 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RISKPHLRSI SIQCYLCLLL NSHFLTEAGI HVFILGCFSA GLPKTEANWV
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against IL15. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL15
- Top Product
- Discover our top product IL15 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 162 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- IL-15 (IL15) (Interleukin 15 (IL15))
- 别名
- IL15 (IL15 产品)
- 别名
- IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody
- 背景
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IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Alias Symbols: IL-15, MGC9721
Protein Interaction Partner: ZNRD1, TRAF3, STAT5B, APP, IL15RA, IL2RG, IL2RB,
Protein Size: 162 - 分子量
- 13 kDa
- 基因ID
- 3600
- NCBI登录号
- NM_172174, NP_751914
- UniProt
- P40933
- 途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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