IL-15 抗体 (N-Term)
Quick Overview for IL-15 抗体 (N-Term) (ABIN2786287)
抗原
See all IL-15 (IL15) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RISKPHLRSI SIQCYLCLLL NSHFLTEAGI HVFILGCFSA GLPKTEANWV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against IL15. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL15
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anti-Interleukin 15 (IL15) (AA 50-162) antibody
IL15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 48-162) antibodyIL15 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 1-162) antibodyIL15 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 15 (IL15) (AA 30-129) antibodyIL15 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Interleukin 15 (IL15) (AA 49-162) antibodyIL15 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Interleukin 15 (IL15) (AA 46-162) antibodyIL15 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Interleukin 15 (IL15) antibodyIL15 适用: 人 WB, ELISA, IP, Func, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 162 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL-15 (IL15) (Interleukin 15 (IL15))
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别名
- IL15
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背景
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IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
Alias Symbols: IL-15, MGC9721
Protein Interaction Partner: ZNRD1, TRAF3, STAT5B, APP, IL15RA, IL2RG, IL2RB,
Protein Size: 162 -
分子量
- 13 kDa
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基因ID
- 3600
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NCBI登录号
- NM_172174, NP_751914
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UniProt
- P40933
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途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
抗原
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