FBXW8 抗体 (Middle Region)
(1 reference)Quick Overview for FBXW8 抗体 (Middle Region) (ABIN2786275)
抗原
See all FBXW8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- MNQKLWEVYS GHPVQHISFS SHSLITANVP YQTVMRNADL DSFTTHRRHR
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预测反应
- Cow: 83%, Dog: 92%, Guinea Pig: 83%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against FBXW8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FBXW8
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anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 270-299) antibody
FBXW8 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28550 unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 499-598) antibodyFBXW8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 273-303), (Middle Region) antibodyFBXW8 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) antibodyFBXW8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) antibodyFBXW8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (C-Term) antibodyFBXW8 适用: 人, Cow, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 8 (FBXW8) (AA 504-553) antibodyFBXW8 适用: 人, Cow, 兔, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 598 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." in: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).
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: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." in: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).
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- FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
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别名
- FBXW8
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背景
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FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6
Protein Interaction Partner: MAP4K1, CUL1, TBC1D3, CUL7, UBE2D3, SKP1, IRS1, REST, CCND1, CUL4A, DDB1, UBC, CCDC8, GORASP1, OBSL1, CCT6B, CCT2, CCT7, TRIP13, PDCD5, CUL2, VBP1, CCT3, PFDN5, NFKBIA, CCT6A, BCL3, BTRC, SKP2, HSP90AA1, HSPA4, FBXO4, FBXW8, FBXW2, MYC, RBX1, UBI4, EP300,
Protein Size: 598 -
分子量
- 67 kDa
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基因ID
- 26259
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NCBI登录号
- NM_153348, NP_699179
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UniProt
- Q8N3Y1
抗原
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