NKIRAS1 抗体 (N-Term)
Quick Overview for NKIRAS1 抗体 (N-Term) (ABIN2786171)
抗原
See all NKIRAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against NKIRAS1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NKIRAS1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 192 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
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别名
- NKIRAS1
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背景
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NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Alias Symbols: KBRAS1, kappaB-Ras1
Protein Interaction Partner: XRCC2, UBC, APP, NFKBIB, SMURF2, BMPR1B, TGFBR1, NFKBIA, ACVR1,
Protein Size: 192 -
分子量
- 22 kDa
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基因ID
- 28512
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NCBI登录号
- NM_020345, NP_065078
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UniProt
- Q9NYS0
抗原
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