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AGTPBP1 抗体 (C-Term)

AGTPBP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786096
发货至: 中国
  • 抗原 See all AGTPBP1 抗体
    AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))
    抗原表位
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 28
    • 13
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠
    宿主
    • 21
    • 6
    • 1
    克隆类型
    • 24
    • 4
    多克隆
    标记
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    This AGTPBP1 antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    GMQPLMYSVQ EALNARPWWI RMGTDICYYK NHFSRSSVAA GGQKGKSYYT
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against Agtpbp1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Agtpbp1
    Top Product
    Discover our top product AGTPBP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1160 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))
    别名
    Agtpbp1 (AGTPBP1 产品)
    别名
    ccp1 antibody, AGTPBP1 antibody, CCP1 antibody, NNA1 antibody, 1700020N17Rik antibody, 2310001G17Rik antibody, 2900054O13Rik antibody, 4930445M19Rik antibody, 5730402G09Rik antibody, BB114605 antibody, Nna1 antibody, mKIAA1035 antibody, nmf243 antibody, pcd antibody, si:ch73-236b16.2 antibody, ATP/GTP binding protein 1 L homeolog antibody, ATP/GTP binding protein 1 antibody, agtpbp1.L antibody, AGTPBP1 antibody, agtpbp1 antibody, Agtpbp1 antibody
    背景
    Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.
    Alias Symbols: 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, BB114605, CCP1, Nna1, mKIAA1035, nmf243, pcd
    Protein Size: 1160
    分子量
    128 kDa
    基因ID
    67269
    NCBI登录号
    NM_023328, NP_075817
    途径
    Proton Transport
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