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AGTPBP1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects AGTPBP1 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼 和 豚鼠.
产品编号 ABIN2786096
发货至: 中国
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Quick Overview for AGTPBP1 抗体 (C-Term) (ABIN2786096)

抗原

See all AGTPBP1 抗体
AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This AGTPBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    GMQPLMYSVQ EALNARPWWI RMGTDICYYK NHFSRSSVAA GGQKGKSYYT

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

    产品特性

    This is a rabbit polyclonal antibody against Agtpbp1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Agtpbp1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1160 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

    别名

    Agtpbp1

    背景

    Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.
    Alias Symbols: 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, BB114605, CCP1, Nna1, mKIAA1035, nmf243, pcd
    Protein Size: 1160

    分子量

    128 kDa

    基因ID

    67269

    NCBI登录号

    NM_023328, NP_075817

    途径

    Proton Transport
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