SPG20 抗体 (Middle Region)
Quick Overview for SPG20 抗体 (Middle Region) (ABIN2786078)
抗原
See all SPG20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ASWVSWGLVK GAEITGKAIQ KGASKLRERI QPEEKPVEVS PAVTKGLYIA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against SPG20. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SPG20
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anti-Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (AA 18-45), (N-Term) antibody
SPG20 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22531 unconjugated
anti-Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (AA 24-54), (N-Term) antibodySPG20 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (AA 431-480) antibodySPG20 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Spastic Paraplegia 20 (Troyer Syndrome) (SPG20) (AA 1-350) antibodySPG20 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 666 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
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别名
- SPG20
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背景
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This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Alias Symbols: KIAA0610, SPARTIN, TAHCCP1
Protein Interaction Partner: UBC, WWOX, ITCH, PLIN3, SMURF2, ZFYVE9, APP, EPS15, SMURF1, WWP2, WWP1, SUMO2, KLC2, AIFM1, VIM, NCL, LMNB1, KPNB1, KIF5B, HSPD1, HSPA9, HSPA5, HADHA, ACSL4, ACSL3, DYNC1H1, COPA, CLTC, TUBA1A,
Protein Size: 666 -
分子量
- 73 kDa
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基因ID
- 23111
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NCBI登录号
- NM_015087, NP_055902
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UniProt
- Q8N0X7
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途径
- Regulation of Cell Size, SARS-CoV-2 Protein Interactome
抗原
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