Spartin (SPART) (Middle Region) 抗体
Our Local Distributor
北京 101111
Quick Overview for Spartin (SPART) (Middle Region) 抗体 (ABIN2786078)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- SPART Antibody - middle region
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序列
- ASWVSWGLVK GAEITGKAIQ KGASKLRERI QPEEKPVEVS PAVTKGLYIA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against SPG20. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SPG20
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anti-Spartin (SPART) (Internal Region) antibody
Verified SPART 适用: 人 ELISA, WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-Spartin (SPART) (AA 205-631) antibodySPART 适用: 人, 大鼠 FACS, ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55162-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Spartin (SPART)
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别名
- SPART
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背景
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Background Information: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Gene Name: spartin
Alternative Symbols: SPG20, TAHCCP1
Protein Name: spartin
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分子量
- 73kDa
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基因ID
- 23111
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NCBI登录号
- NP_055902
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UniProt
- Q8N0X7
抗原
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