HSPB8 抗体 (N-Term)
Quick Overview for HSPB8 抗体 (N-Term) (ABIN2786018)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ADGQMPFSCH YPSRLRRDPF RDSPLSSRLL DDGFGMDPFP DDLTASWPDW
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预测反应
- Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against HSPB8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSPB8
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anti-Heat Shock 22kDa Protein 8 (HSPB8) (AA 1-196) antibody
HSPB8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibodyHSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock 22kDa Protein 8 (HSPB8) (AA 97-196) antibodyHSPB8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5B12 unconjugated
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (HRP)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal HRP
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (FITC)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal FITC
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (Biotin)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal Biotin
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (PE)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal PE
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (APC)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal APC
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (PerCP)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal PerCP
anti-Heat Shock 22kDa Protein 8 (HSPB8) antibody (Atto 488)HSPB8 适用: 人 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal Atto 488
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 196 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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别名
- HSPB8
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背景
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HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Protein Interaction Partner: QRICH1, HSPB7, DUSP12, BAG3, ASB4, UBC, CIAPIN1, DSTN, HSPB6, HSPB3, SNCA, CRYAB, HSPB1, HSPB8, MAPK3, PRKCA, CSNK2A1, HSPB2,
Protein Size: 196 -
分子量
- 21 kDa
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基因ID
- 26353
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NCBI登录号
- NM_014365, NP_055180
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UniProt
- Q9UJY1
抗原
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