ORC6 抗体 (N-Term)
Quick Overview for ORC6 抗体 (N-Term) (ABIN2786007)
抗原
See all ORC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KAEEYLRLSR VKCVGLSART TETSSAVMCL DLAASWMKCP LDRAYLIKLS
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预测反应
- Cow: 92%, Dog: 100%, Horse: 77%, Human: 100%, Rabbit: 85%
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产品特性
- This is a rabbit polyclonal antibody against ORC6. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ORC6
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anti-Origin Recognition Complex, Subunit 6 (ORC6) (AA 1-252) antibody
ORC6 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) (AA 1-252) antibodyORC6 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) (AA 1-252) antibodyORC6 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) (AA 1-252) antibodyORC6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) antibodyORC6 适用: 人 WB, IP, ChIP 宿主: 大鼠 Monoclonal 3A4 unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) (C-Term) antibodyVerified ORC6 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) (C-Term) antibodyORC6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) antibodyORC6 适用: 人 DB, ICC 宿主: 小鼠 Monoclonal 2679C2b unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) antibodyORC6 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 6 (ORC6) (C-Term) antibodyORC6 适用: 人, 小鼠, 犬, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
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别名
- ORC6
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背景
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The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC6L is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
Alias Symbols: ORC6L
Protein Interaction Partner: LHX4, SPAG5, UBC, ORC3, CDC7, ORC4, MCM7, MCM6, MCM4, MCM2, CDC6, APP, ORC2, SUMO2, XRCC5, XRCC6, HMGA1, MCM5, TERF2, ORC5, DBF4, CDC45, RPA1,
Protein Size: 252 -
分子量
- 28 kDa
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基因ID
- 23594
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NCBI登录号
- NM_014321, NP_055136
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UniProt
- Q9Y5N6
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途径
- Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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