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ORC6 抗体 (N-Term)

ORC6 适用: 人, 犬, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786007
发货至: 中国
  • 抗原 See all ORC6 抗体
    ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
    抗原表位
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 24
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 犬, Cow, 马, 兔
    宿主
    • 14
    • 7
    • 2
    • 1
    克隆类型
    • 17
    • 7
    多克隆
    标记
    • 24
    This ORC6 antibody is un-conjugated
    应用范围
    • 21
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    KAEEYLRLSR VKCVGLSART TETSSAVMCL DLAASWMKCP LDRAYLIKLS
    预测反应
    Cow: 92%, Dog: 100%, Horse: 77%, Human: 100%, Rabbit: 85%
    产品特性
    This is a rabbit polyclonal antibody against ORC6. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human ORC6
    Top Product
    Discover our top product ORC6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
    别名
    ORC6 (ORC6 产品)
    背景
    The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC6L is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
    Alias Symbols: ORC6L
    Protein Interaction Partner: LHX4, SPAG5, UBC, ORC3, CDC7, ORC4, MCM7, MCM6, MCM4, MCM2, CDC6, APP, ORC2, SUMO2, XRCC5, XRCC6, HMGA1, MCM5, TERF2, ORC5, DBF4, CDC45, RPA1,
    Protein Size: 252
    分子量
    28 kDa
    基因ID
    23594
    NCBI登录号
    NM_014321, NP_055136
    UniProt
    Q9Y5N6
    途径
    Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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