VPS4A 抗体 (N-Term)
(1 reference)Quick Overview for VPS4A 抗体 (N-Term) (ABIN2785950)
抗原
See all VPS4A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- YFLHAIKYEA HSDKAKESIR AKCVQYLDRA EKLKDYLRSK EKHGKKPVKE
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against VPS4A. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human VPS4A
-
-
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 1-120) antibody
VPS4A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) antibodyVPS4A 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 44-77), (N-Term) antibodyVPS4A 适用: 人 WB 宿主: 兔 Polyclonal RB49739 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 1-437) antibodyVPS4A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 74-123) antibodyVPS4A 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 38-87) antibodyVPS4A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 斑马鱼, Hamster, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 437 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding." in: Journal of virology, Vol. 81, Issue 24, pp. 13631-9, (2007) (PubMed).
-
: "Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding." in: Journal of virology, Vol. 81, Issue 24, pp. 13631-9, (2007) (PubMed).
-
- VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
-
别名
- VPS4A
-
背景
-
VPS4A is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast.The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ22197, SKD1, SKD2, VPS4, VPS4-1, SKD1A
Protein Interaction Partner: FBXO6, UBC, CFTR, KCND3, CHMP4B, CHMP1B, CHMP4A, CHMP2A, VPS4A, CHMP1A, CHMP4C, gag, VTA1, CHMP3, CHMP5, HGS, NPC1, BABAM1, VPS4B, RND2,
Protein Size: 437 -
分子量
- 49 kDa
-
基因ID
- 27183
-
NCBI登录号
- NM_013245, NP_037377
-
UniProt
- Q9UN37
-
途径
- Microtubule Dynamics, CXCR4-mediated Signaling Events
抗原
-
