GTPBP4 抗体 (C-Term)
Quick Overview for GTPBP4 抗体 (C-Term) (ABIN2785935)
抗原
See all GTPBP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- MVKKAKTMMK NAQKKMNRLG KKGEADRHVF DMKPKHLLSG KRKAGKKDRR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against GTPBP4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GTPBP4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 634 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GTPBP4 (GTP Binding Protein 4 (GTPBP4))
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别名
- GTPBP4
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背景
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GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Alias Symbols: CRFG, FLJ10686, FLJ10690, FLJ39774, NGB, NOG1
Protein Interaction Partner: SUMO3, UBC, POP1, PNMA2, PSME3, PRKRA, SUMO1, STAU1, NEDD8, EIF6, IFRD1, AZGP1, MRTO4, KCTD2, DICER1, SUZ12, EED, RNF2, CSNK2A2, CBX8, VCAM1, FN1, ESR1, UBD, CAND1, COPS5, SIRT7, SUMO2, EIF2AK2, OAS3, tat, TP53, YWHAG, LYAR, PINX1,
Protein Size: 634 -
分子量
- 74 kDa
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基因ID
- 23560
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NCBI登录号
- NM_012341, NP_036473
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UniProt
- Q9BZE4
抗原
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