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GTPBP4 抗体 (C-Term)

This anti-GTPBP4 antibody is a 兔 多克隆 antibody detecting GTPBP4 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 兔 和 豚鼠.
产品编号 ABIN2785935
发货至: 中国

Quick Overview for GTPBP4 抗体 (C-Term) (ABIN2785935)

抗原

See all GTPBP4 抗体
GTPBP4 (GTP Binding Protein 4 (GTPBP4))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠

宿主

  • 21
  • 2

克隆类型

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  • 2
多克隆

标记

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This GTPBP4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    MVKKAKTMMK NAQKKMNRLG KKGEADRHVF DMKPKHLLSG KRKAGKKDRR

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against GTPBP4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human GTPBP4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 634 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GTPBP4 (GTP Binding Protein 4 (GTPBP4))

    别名

    GTPBP4

    背景

    GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
    Alias Symbols: CRFG, FLJ10686, FLJ10690, FLJ39774, NGB, NOG1
    Protein Interaction Partner: SUMO3, UBC, POP1, PNMA2, PSME3, PRKRA, SUMO1, STAU1, NEDD8, EIF6, IFRD1, AZGP1, MRTO4, KCTD2, DICER1, SUZ12, EED, RNF2, CSNK2A2, CBX8, VCAM1, FN1, ESR1, UBD, CAND1, COPS5, SIRT7, SUMO2, EIF2AK2, OAS3, tat, TP53, YWHAG, LYAR, PINX1,
    Protein Size: 634

    分子量

    74 kDa

    基因ID

    23560

    NCBI登录号

    NM_012341, NP_036473

    UniProt

    Q9BZE4
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