KPNA6 抗体 (N-Term)
Quick Overview for KPNA6 抗体 (N-Term) (ABIN2785933)
抗原
See all KPNA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- STTGESVITR EMVEMLFSDD SDLQLATTQK FRKLLSKEPS PPIDEVINTP
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against KPNA6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA6
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anti-Karyopherin alpha 6 (Importin alpha 7) (KPNA6) (AA 277-536) antibody
KPNA6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 6 (Importin alpha 7) (KPNA6) (Internal Region) antibodyVerified KPNA6 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin alpha 6 (Importin alpha 7) (KPNA6) (AA 101-200) antibodyKPNA6 适用: 人, 小鼠 WB, ELISA, IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 6 (Importin alpha 7) (KPNA6) (AA 74-123) antibodyKPNA6 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 536 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
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别名
- KPNA6
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背景
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The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. KPNA6 is a member of the importin alpha family.Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ11249, IPOA7, KPNA7, MGC17918
Protein Interaction Partner: FRG1B, NUP50, UBC, NOP2, XRN2, rev, TTC1, PRKAR2A, LMNA, KPNA3, KPNA2, GFPT1, HDAC1, SKP2, CDKN1B, KPNB1, ZNF131, ANP32A, TAF9, CUL3, ELAVL1, KEAP1, Nipbl, Ddx21, Nhp2l1, Mki67, CREBBP, RAC1, MEPCE, RELB, CSE1L, STAT1, BRCA1, STAT3, SPOP,
Protein Size: 536 -
分子量
- 60 kDa
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基因ID
- 23633
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NCBI登录号
- NM_012316, NP_036448
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UniProt
- O60684
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途径
- Protein targeting to Nucleus
抗原
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