PTGR1 抗体 (N-Term)
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北京 101111
Quick Overview for PTGR1 抗体 (N-Term) (ABIN2785929)
抗原
See all PTGR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- LTB4DH Antibody - N-terminal region
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序列
- VRTKTWTLKK HFVGYPTNSD FELKTSELPP LKNGEVLLEA LFLTVDPYMR
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预测反应
- Cow: 93%, Guinea Pig: 83%, Horse: 83%, Human: 93%, Rabbit: 83%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against LTB4DH. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LTB4DH
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54865-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase." in: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25626-37, (2013) (PubMed).
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- PTGR1 (Prostaglandin Reductase 1 (PTGR1))
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别名
- LTB4DH
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背景
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Background Information: LTB4DH functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. It has no activity towards PGE1, PGE2 and PGE2-alpha. LTB4DH catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
Gene Name: Prostaglandin reductase 1
Alternative Symbols: PGR1, DIG-1, ZADH3, LTB4DH
Protein Name: Prostaglandin reductase 1
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分子量
- 36kDa
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基因ID
- 22949
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NCBI登录号
- NP_036344
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UniProt
- A8K0N2
抗原
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