FBXO8 抗体 (Middle Region)
Quick Overview for FBXO8 抗体 (Middle Region) (ABIN2785927)
抗原
See all FBXO8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- EFFRHIHAPE ERGEYLETLI TKFSHRFCAC NPDLMRELGL SPDAVYVLCY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against FBXO8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FBXO8
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anti-F-Box Protein 8 (FBXO8) (AA 1-77) antibody
FBXO8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C11 unconjugated
anti-F-Box Protein 8 (FBXO8) antibodyFBXO8 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 8 (FBXO8) (AA 1-77) antibodyFBXO8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 8 (FBXO8) (AA 1-319) antibodyFBXO8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-F-Box Protein 8 (FBXO8) (AA 216-265) antibodyFBXO8 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 8 (FBXO8) (AA 110-250) antibodyFBXO8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 319 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXO8 (F-Box Protein 8 (FBXO8))
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别名
- FBXO8
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背景
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FBXO8 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO8 belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Alias Symbols: DC10, FBS, FBX8
Protein Interaction Partner: SKP1, ELAVL1, MYC, CUL1, UBC, ARF6,
Protein Size: 319 -
分子量
- 37 kDa
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基因ID
- 26269
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NCBI登录号
- NM_012180, NP_036312
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UniProt
- Q9NRD0
抗原
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