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IDH1 抗体 (C-Term)

Name: IDH1 抗体 (C-Term)
SKU: ABIN2785882
Availability: OutOfStock

This anti-IDH1 antibody is a 兔多克隆 antibody detecting IDH1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Saccharomyces cerevisiae, 马, 豚鼠, Cow, 兔和绵羊.

Western Blotting (WB) image for anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (C-Term) antibody (ABIN2785882) (IDH1 抗体 (C-Term))

2 images

产品编号 ABIN2785882

发货至: 中国

Datasheet as PDF

Quick Overview for IDH1 抗体 (C-Term) (ABIN2785882)

抗原

See all IDH1 抗体

IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

适用

人, 小鼠, 大鼠, 犬, Saccharomyces cerevisiae, 马, 豚鼠, Cow, 兔, 绵羊

宿主

兔

克隆类型

多克隆

标记

This IDH1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product IDH1 Primary Antibody

抗原表位
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C-Term

序列

MMTSVLVCPD GKTVEAEAAH GTVTRHYRMY QKGQETSTNP IASIFAWTRG

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%

产品特性

This is a rabbit polyclonal antibody against IDH1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human IDH1
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 1-414) antibody
IDH1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 74-333) antibody
IDH1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 156-298) antibody
IDH1 适用: 人, 小鼠, 猴 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G8A1 unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (N-Term) antibody
IDH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (Center) antibody
IDH1 适用: 人, 小鼠 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 156-298) antibody
IDH1 适用: 人, 小鼠, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4A4A8 unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 381-413), (C-Term) antibody
IDH1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 116-143) antibody
IDH1 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB18238 unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 63-90) antibody
IDH1 适用: 人, 小鼠 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 116-143) antibody
IDH1 适用: 人, 小鼠 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 414 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

别名

IDH1

背景

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IDH, IDP, PICD, IDCD, IDPC
Protein Interaction Partner: SUMO2, UBC, GLRX3, UBE2H, THOP1, TALDO1, RCN1, RBBP7, RANBP1, PTMS, OXCT1, NME1, HSPE1, GOT1, FDPS, DCK, ANXA6, ADSS, NME1-NME2, EFHD2, C12orf10, SBDS, CHMP4A, CBX3, SUGT1, PEX5, AK2, AK1, MDH2, ASF1B, CDK2, SLC2A4, ELAVL1, SUMO4, ZHX1,
Protein Size: 414

分子量

47 kDa

基因ID

3417

NCBI登录号

NM_005896, NP_005887

UniProt

O75874

途径

Warburg Effect