LOXL1 抗体 (N-Term)
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北京 101111
Quick Overview for LOXL1 抗体 (N-Term) (ABIN2785878)
抗原
See all LOXL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RWRQLIQWEN NGQVYSLLNS GSEYVPAGPQ RSESSSRVLL AGAPQAQQRR
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预测反应
- Cow: 83%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against LOXL1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LOXL1
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anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 392-598) antibody
LOXL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 1-574) antibodyLOXL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 1-574) antibodyLOXL1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 369-574) antibodyLOXL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 369-574) antibodyLOXL1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 393-603) antibodyLOXL1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 1-574) antibodyLOXL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 95-370) antibodyLOXL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) (AA 106-574) antibodyLOXL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 1 (LOXL1) antibodyLOXL1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 574 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).
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: "Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).
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- LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
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别名
- LOXL1
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背景
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LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LOL, LOXL
Protein Interaction Partner: ATXN1, CUL2, FBLN5, ELN,
Protein Size: 574 -
分子量
- 53 kDa
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基因ID
- 4016
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NCBI登录号
- NM_005576, NP_005567
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UniProt
- Q08397
抗原
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