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LOXL1 抗体 (N-Term)

This anti-LOXL1 antibody is a 兔 多克隆 antibody detecting LOXL1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 豚鼠 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2785878
发货至: 中国

Quick Overview for LOXL1 抗体 (N-Term) (ABIN2785878)

抗原

See all LOXL1 抗体
LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

适用

  • 55
  • 21
  • 8
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马

宿主

  • 59
  • 7

克隆类型

  • 61
  • 5
多克隆

标记

  • 35
  • 11
  • 10
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LOXL1 antibody is un-conjugated

应用范围

  • 45
  • 26
  • 19
  • 18
  • 15
  • 9
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    RWRQLIQWEN NGQVYSLLNS GSEYVPAGPQ RSESSSRVLL AGAPQAQQRR

    预测反应

    Cow: 83%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against LOXL1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human LOXL1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 574 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ohmura, Yasukawa, Minami, Sugi, Oba, Nagata, Kyogoku, Ohshima, Aoki, Imaizumi: "Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).

  • 抗原

    LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

    别名

    LOXL1

    背景

    LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: LOL, LOXL
    Protein Interaction Partner: ATXN1, CUL2, FBLN5, ELN,
    Protein Size: 574

    分子量

    53 kDa

    基因ID

    4016

    NCBI登录号

    NM_005576, NP_005567

    UniProt

    Q08397
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