ICA1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for ICA1 抗体 (C-Term) (ABIN2785862)
抗原
See all ICA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- ICA1 Antibody - C-terminal region
-
序列
- NMKDLQASLQ EPAKAASDLT AWFSLFADLD PLSNPDAVGK TDKEHELLNA
-
预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against ICA1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ICA1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54743-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
-
-
- ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))
-
别名
- ICA1
-
背景
-
Background Information: ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Gene Name: Islet cell autoantigen 1, 69 kDa
Alternative Symbols: ICA69, ICAp69
Protein Name: Islet cell autoantigen 1
-
分子量
- 53kDa
-
基因ID
- 3382
-
NCBI登录号
- NP_071682
-
UniProt
- Q05084
抗原
-