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ICA1 抗体 (C-Term)

Cited in 1 publication. The 兔 多克隆 anti-ICA1 antibody (ABIN2785862) specifically detects ICA1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow 和 兔 samples.
产品编号 ABIN2785862
发货至: 中国
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Quick Overview for ICA1 抗体 (C-Term) (ABIN2785862)

抗原

See all ICA1 抗体
ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

适用

  • 73
  • 24
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  • 1
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人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔

宿主

  • 70
  • 8
兔

克隆类型

  • 73
  • 5
多克隆

标记

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  • 12
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This ICA1 antibody is un-conjugated

应用范围

  • 57
  • 17
  • 17
  • 13
  • 13
  • 9
  • 6
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 12
    • 8
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    • 5
    • 3
    • 2
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    • 2
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    • 2
    • 1
    C-Term

    原理

    ICA1 Antibody - C-terminal region

    序列

    NMKDLQASLQ EPAKAASDLT AWFSLFADLD PLSNPDAVGK TDKEHELLNA

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ICA1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human ICA1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54743-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

    别名

    ICA1

    背景

    Background Information: ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.

    Gene Name: Islet cell autoantigen 1, 69 kDa

    Alternative Symbols: ICA69, ICAp69

    Protein Name: Islet cell autoantigen 1

    分子量

    53kDa

    基因ID

    3382

    NCBI登录号

    NP_071682

    UniProt

    Q05084
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