ICA1 抗体 (C-Term)
Quick Overview for ICA1 抗体 (C-Term) (ABIN2785862)
抗原
See all ICA1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            序列
- NMKDLQASLQ EPAKAASDLT AWFSLFADLD PLSNPDAVGK TDKEHELLNA
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                                            预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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                                            产品特性
- This is a rabbit polyclonal antibody against ICA1. It was validated on Western Blot using a cell lysate as a positive control.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ICA1
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
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                        Antigen size: 483 AA 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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                                            : "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..."    in: Molecular systems biology, Vol. 3, pp. 89, (2007)         (PubMed).        
 
 
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                                            : "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..."    in: Molecular systems biology, Vol. 3, pp. 89, (2007)         (PubMed).        
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    - ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))
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                                            别名
- ICA1
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                                            背景
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                        ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
 Alias Symbols: ICA69, ICAp69
 Protein Interaction Partner: RAB2B, ING5, MBD3, CCDC28A, RAB2A, tbc-8, EXOC5, STK16, MKKS, KRT33B, CNTF,
 Protein Size: 483
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                                            分子量
- 53 kDa
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                                            基因ID
- 3382
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                                            NCBI登录号
- NM_022307, NP_071682
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                                            UniProt
- Q05084
 抗原
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