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ICA1 抗体 (N-Term)

This anti-ICA1 antibody is a 兔 多克隆 antibody detecting ICA1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2785861
发货至: 中国

Quick Overview for ICA1 抗体 (N-Term) (ABIN2785861)

抗原

See all ICA1 抗体
ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

适用

  • 63
  • 15
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔, 斑马鱼

宿主

  • 63
  • 7

克隆类型

  • 64
  • 6
多克隆

标记

  • 31
  • 12
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ICA1 antibody is un-conjugated

应用范围

  • 60
  • 21
  • 20
  • 13
  • 13
  • 11
  • 6
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    SKAIVLYQKR ICFLSQEENE LGKFLRSQGF QDKTRAGKMM QATGKALCFS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against ICA1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ICA1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 483 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))

    别名

    ICA1

    背景

    ICA1 is a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
    Alias Symbols: ICA69, ICAp69
    Protein Interaction Partner: RAB2B, ING5, MBD3, CCDC28A, RAB2A, tbc-8, EXOC5, STK16, MKKS, KRT33B, CNTF,
    Protein Size: 483

    分子量

    55 kDa

    基因ID

    3382

    NCBI登录号

    NM_004968, NP_004959

    UniProt

    Q05084
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