RHOB 抗体 (Middle Region)
Quick Overview for RHOB 抗体 (Middle Region) (ABIN2785839)
抗原
See all RHOB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- CPNVPIILVA NKKDLRSDEH VRTELARMKQ EPVRTDDGRA MAVRIQAYDY
-
预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Sheep: 100%, Zebrafish: 79%
-
产品特性
- This is a rabbit polyclonal antibody against RHOB. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RHOB
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 196 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
-
别名
- RHOB
-
背景
-
RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Alias Symbols: ARH6, ARHB, MST081, MSTP081, RHOH6
Protein Interaction Partner: RAC1, MDM2, UBC, CORO1C, LAMTOR3, ILF2, HNRNPU, TNFAIP1, ELAVL1, ARHGEF3, RHPN2, PPP2CA, ARHGDIG, PDE6D, PGGT1B, FNTA, CIT,
Protein Size: 196 -
分子量
- 22 kDa
-
基因ID
- 388
-
NCBI登录号
- NM_004040, NP_004031
-
UniProt
- P62745
抗原
-