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LYN 抗体 (N-Term)

Name: LYN 抗体 (N-Term)
SKU: ABIN2785837
Availability: OutOfStock

This anti-LYN antibody is a 兔多克隆 antibody detecting LYN in WB. Suitable for 人, 小鼠, 大鼠, Cow, 绵羊, Pig, 犬, 豚鼠, 马和兔.

Host: Rabbit Target Name: LYN Sample Tissue: Human Fetal Brain Antibody Dilution: 1. (LYN 抗体 (N-Term))

Host: Rabbit Target Name: LYN Sample Tissue: Human Fetal Heart Antibody Dilution: 1. (LYN 抗体 (N-Term))

Host: Rabbit Target Name: LYN Sample Tissue: Human Fetal Lung Antibody Dilution: 1. (LYN 抗体 (N-Term))

3 images

产品编号 ABIN2785837

发货至: 中国

Datasheet as PDF

Quick Overview for LYN 抗体 (N-Term) (ABIN2785837)

抗原

See all LYN 抗体

LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

适用

人, 小鼠, 大鼠, Cow, 绵羊, Pig, 犬, 豚鼠, 马, 兔

宿主

兔

克隆类型

多克隆

标记

This LYN antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product LYN Primary Antibody

抗原表位
22

16

9

8

8

5

5

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4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

序列

DPTSNKQQRP VPESQLLPGQ RFQTKDPEEQ GDIVVALYPY DGIHPDDLSF

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

产品特性

This is a rabbit polyclonal antibody against LYN. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human LYN
anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (pTyr507) antibody
LYN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (C-Term) antibody
LYN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (Center) antibody
LYN 适用: 人 WB, IP, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (AA 229-263) antibody
LYN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (AA 32-62) antibody
LYN 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (AA 470-501) antibody
LYN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (pTyr397) antibody
LYN 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (pTyr508) antibody
LYN 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 犬, 豚鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (AA 229-263) antibody
LYN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50588 unconjugated

anti-V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) (AA 39-58) antibody
LYN 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 512 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

别名

LYN

背景

LYN down regulates expression of stem cell growth factor receptor (KIT).LYN acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation.LYN acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. LYN acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. Involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents.LYN induces SAPK by a MKK7- and MEKK1-dependent mechanism. The LYN -> MEKK1 -> MKK7 -> SAPK pathway is functional in the induction of apoptosis by genotoxic agents.
Alias Symbols: FLJ26625, JTK8, p53Lyn, p56Lyn
Protein Interaction Partner: UBC, IKBKG, TRIM28, EGFR, RGS16, TNF, IL1B, ANGPT2, DKFZP434K028, CNOT10, TGDS, CBX6, FBXO28, ZNF423, RASSF8, FRS2, HBS1L, TUBB4A, SH2D3C, RIMS2, DDX21, KYNU, TNFSF12, PIK3R3, YEATS4, ZNF189, UGP2, HSP90B1, TADA2A, SLC12A4, RDX, PRKCB, SCIMP, LNP1, RNF180
Protein Size: 512

分子量

58 kDa

基因ID

4067

NCBI登录号

NM_002350, NP_002341

UniProt

P07948

途径

Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling