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LIF 抗体 (N-Term)

This anti-LIF antibody is a 兔 多克隆 antibody detecting LIF in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2785833
发货至: 中国

Quick Overview for LIF 抗体 (N-Term) (ABIN2785833)

抗原

See all LIF 抗体
LIF (Leukemia Inhibitory Factor (LIF))

适用

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人, 小鼠, 大鼠, 犬, Cow, 绵羊, 豚鼠, 马, 兔

宿主

  • 49
  • 18
  • 2
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  • 1
  • 1
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克隆类型

  • 57
  • 17
多克隆

标记

  • 62
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This LIF antibody is un-conjugated

应用范围

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  • 2
  • 1
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Western Blotting (WB)
  • 抗原表位

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    • 1
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    N-Term

    序列

    KVLAAGVVPL LLVLHWKHGA GSPLPITPVN ATCAIRHPCH NNLMNQIRSQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 86%

    产品特性

    This is a rabbit polyclonal antibody against LIF. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human LIF
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 202 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Muntz, Malpass, McGonigle, Robertson, Weiden: "Phase 2 study of intraperitoneal topotecan as consolidation chemotherapy in ovarian and primary peritoneal carcinoma." in: Cancer, Vol. 113, Issue 3, pp. 490-6, (2008) (PubMed).

  • 抗原

    LIF (Leukemia Inhibitory Factor (LIF))

    别名

    LIF

    背景

    LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.Leukaemia inhibitory factor is a cytokine that induces macrophage differentiation. Neurotransmitters and neuropeptides, well known for their role in the communication between neurons, are also capable of activating monocytes and macrophages and inducing chemotaxis in immune cells. LIF signals through different receptors and transcription factors. LIF in conjunction with BMP2 acts in synergy on primary fetal neural progenitor cells to induce astrocytes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CDF, D-FACTOR, HILDA, DIA
    Protein Interaction Partner: IL6ST, LIFR,
    Protein Size: 202

    分子量

    22 kDa

    基因ID

    3976

    NCBI登录号

    NM_002309, NP_002300

    UniProt

    P15018

    途径

    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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