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ARF6 抗体 (Middle Region)

This anti-ARF6 antibody is a 兔 多克隆 antibody detecting ARF6 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔, 绵羊 和 犬. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2785790
发货至: 中国

Quick Overview for ARF6 抗体 (Middle Region) (ABIN2785790)

抗原

See all ARF6 抗体
ARF6 (ADP-Ribosylation Factor 6 (ARF6))

适用

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人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔, 绵羊, 犬

宿主

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克隆类型

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多克隆

标记

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This ARF6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    REMRDAIILI FANKQDLPDA MKPHEIQEKL GLTRIRDRNW YVQPSCATSG

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against ARF6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ARF6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 175 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tagliatti, Fadda, Falace, Benfenati, Fassio: "Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse." in: eLife, Vol. 5, (2016) (PubMed).

  • 抗原

    ARF6 (ADP-Ribosylation Factor 6 (ARF6))

    别名

    ARF6

    背景

    ARF6 is a member of the human ARF family, which is part of the RAS superfamily. They are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF6 is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DKFZp564M0264
    Protein Interaction Partner: UBC, LSB5, GGA1, STAU1, EGFR, CYTH1, CYTH2, GNAQ, FN1, VCP, APP, RAB11FIP3, RAB11FIP4, RAB11FIP5, USP6, IKBKG, GGA3, ITSN1, ASAP1, FBXO8, MEPCE, RUVBL2, ASAP3, MPP5, ZNF709, EXOC5, ARFIP2, AP3D1, PIP5K1C, ASAP2, AP3B1, PIP5K1A, PLD1, AP1B1, EZR, CHRM3, CA
    Protein Size: 175

    分子量

    20 kDa

    基因ID

    382

    NCBI登录号

    NM_001663, NP_001654

    UniProt

    P62330

    途径

    Steroid Hormone Mediated Signaling Pathway, Regulation of Actin Filament Polymerization, SARS-CoV-2 Protein Interactome
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